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Email this article Does structural MRI correlate with a stage of Alzheimer’s disease – a case report.
Abstract
Background: Cortical atrophy is discussed as a topographical marker of the Alzheimer's disease (AD). Structural MRI has been shown to be sensitive in detecting brain changes associated with AD. However, data are conflicting regarding the correlation of MRI findings with the clinical stage of AD.
Case presentation: Here, we report the case of a 74-year-old white woman presented initially with predominantly cognitive complains. AD in a stage between mild and moderate was suspected. In contrast, MRI showed bilateral severe atrophy of entorhinal cortex and hippocampus. Within following seven months disease progressed with development of psychosis. We suggest that clinical presentation and neuroimaging data were dissociated at the first presentation in neurology setting.
Conclusions: This case represents an interesting presentation which brings arguments into hypothesis of predictive value of neuroimaging data for diagnosis of AD
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ISSN: 2346-8491 (online)